The Alliance of Mayors and Municipal Leaders’ Initiative for Community Action on AIDS at the Local Level (AMICAALL) is an association of African Mayors and other Urban Leaders formed to support sustainable solutions to the HIV and AIDS epidemic in African Cities and Municipalities. AMICAALL Uganda Chapter was launched on 28th November 2000 at the Mayors’ Parlour City Hall – Kampala where Ugandan Mayors, under the leadership of Kampala Capital City signed the Kampala Declaration to promote actions that contribute to limiting the spread of HIV and alleviate the social and economic impact of the epidemic on urban and peri-urban communities in Uganda. The chapter has since registered and operated as a National Non-Government Organization primarily targeting urban local governments in the National HIV/AIDS response and spearheads the urban HIV and AIDS response. Because of its uniqueness of being the only urban-focused non-governmental organization with the mandate of urban local governments to coordinate their response, AMICAALL leverages on its mandate to strengthen the capacity of the Mayors, other elected urban Local Government Leaders as well as technical leaders to coordinate the decentralized urban HIV&AIDS response, play an oversight, stewardship and accountability role, planning and resource mobilization, advocacy and lobby, community mobilization and demand creation in order to ensure effective and efficient delivery of HIV/AIDS and other health services.